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Depression: Just Say NO

Depression is a common psychiatric disorder that has a twofold higher prevalence in women compared with men. The underlying mechanism of this “gender gap” in depression remains elusive.

Now, Hu and colleagues provide new insight into the role of the signaling molecule nitric oxide (NO) in pathways leading to affective disorders.

They focused on NO production in the hippocampus, a brain structure important for memory formation……

http://stm.sciencemag.org/content/4/151/151ec165

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